I grew up in Italy, where pasta isn’t just food—it’s a way of life. For me, lasagna has always been the ultimate comfort dish, layered with love and full of flavor. I have pasta in my blood, and I still believe that every bite of a good lasagna should feel like a celebration at the table.
While the classic recipe is already extraordinary, what excites me most is bringing something new to the plate—adding a different twist to enhance a dish that’s already exceptional. That’s how this Chicken Alfredo Lasagna was born: a creamy, hearty fusion between traditional Italian layers and the rich, velvety comfort of Alfredo sauce.
This version keeps the soul of lasagna—those tender lasagna noodles, gooey mozzarella cheese, and the irresistible baked golden top—but transforms it with juicy chicken, a creamy homemade Alfredo sauce, and a subtle hint of pesto for a modern touch. The result? A dish that’s cozy, elegant, and unforgettable.
Whether you grew up loving classic lasagna or you’re just discovering new ways to enjoy pasta, this recipe brings you the best of both worlds. It’s indulgent without being complicated, perfect for family dinners, date nights, or anytime you want to serve a dish that feels both familiar and exciting.
If you love easy chicken recipes that still taste special, this chicken Alfredo lasagna recipe will become a favorite. It’s a dish you’ll want to bake again and again—not only because it’s simple to prepare, but because every layer is full of flavor and warmth.
What Makes This Chicken Alfredo Lasagna So Special
There are many reasons why this chicken Alfredo lasagna recipe deserves a place on your table, and once you try it, you’ll understand why it’s a keeper.
- A creamy twist on a classic Instead of the traditional red sauce, this recipe uses a rich, homemade Alfredo sauce. The result is a white lasagna that feels lighter yet indulgent, with layers that melt together in the most comforting way.
- Easy chicken, maximum flavor Using rotisserie chicken or pre-cooked chicken saves time without sacrificing taste. It makes this dish incredibly easy to prepare while still delivering the deep, savory flavors of a classic lasagna.
- Perfect for gatherings This lasagna is made to be shared. It’s hearty enough to feed a family, yet elegant enough for special occasions. Serve it at a dinner party or a cozy family night, and it’s guaranteed to impress.
- Flexible and customizable You can add spinach for extra greens, use oven-ready lasagna noodles to cut prep time, or play with cheeses like smoked mozzarella or ricotta. This recipe adapts to your taste while staying delicious.
- Comfort food with a twist Lasagna is the definition of comfort food, and this Alfredo version brings something unexpected to the table. It’s creamy, golden, and absolutely irresistible—proof that even the classics can be reimagined.
Gather These Simple Ingredients for Alfredo Chicken Lasagna
For the Alfredo sauce
4 tablespoons butter
4 garlic cloves, minced
¼ cup all-purpose flour
2 cups whole milk
1 cup chicken broth
1 cup heavy cream
1 cup freshly grated Parmesan cheese
1 teaspoon salt (adjust to taste)
½ teaspoon black pepper
For the lasagna layers
12 lasagna noodles (classic or oven-ready)
3 cups cooked chicken, shredded (about 2 large chicken breasts or 1 rotisserie chicken)
2 cups ricotta cheese
3 cups shredded mozzarella cheese
2 cups baby spinach leaves (or 1 cup frozen spinach, completely thawed and thoroughly squeezed dry)
3 tablespoons pesto (optional fusion twist for extra flavor)
For assembly and baking
2 tablespoons olive oil (to drizzle and prevent sticking)
½ cup grated Parmesan cheese (for topping)
Aluminum foil (to cover during baking)
How to Make the Creamiest Chicken Alfredo Lasagna
Step 1: Prepare the Alfredo sauce
Heat a large skillet over medium heat. Add the butter and let it melt completely.
Add the minced garlic and sauté gently for 2–3 minutes, letting its aroma fill your kitchen.
Whisk in the flour gradually to form a silky roux. Let it cook for a full minute to eliminate any raw flour flavor.
Slowly pour in the milk and chicken broth, whisking continuously to create a silky smooth base.
Pour in the heavy cream and let the mixture come to a luxurious, gentle simmer.
Fold in the Parmesan cheese, whisking until it completely melts into a velvety sauce.
Season thoughtfully with salt and pepper, then set aside.
Step 2: Cook the lasagna noodles
If using classic lasagna noodles: bring a large pot of salted water to a boil.
Add the noodles and cook until perfectly al dente (about 8 minutes). Drain, drizzle with olive oil, and set aside.
For oven-ready noodles, simply keep them aside—no pre-cooking needed.
Step 3: Prepare the chicken filling
Shred the cooked chicken into bite-sized pieces.
In a bowl, combine shredded chicken with ½ cup of Alfredo sauce and 2 tablespoons pesto (if using).
Mix well so the chicken is coated and flavorful.
Step 4: Assemble the lasagna
Preheat your oven to 375°F (190°C).
Generously coat a 9×13-inch baking dish with olive oil to prevent sticking.
Create a foundation by spreading a thin, even layer of Alfredo sauce across the bottom.
Add 3 lasagna noodles in a single layer.
Spread ⅓ of the ricotta cheese, ⅓ of the chicken mixture, a handful of spinach, and a sprinkle of mozzarella.
Repeat layering the lasagna (sauce → noodles → ricotta → chicken → spinach → mozzarella) 3 times.
Finish with noodles on top, the remaining Alfredo sauce, shredded mozzarella, and grated Parmesan.
Step 5: Bake the lasagna
Cover the baking dish with aluminum foil (to keep it moist).
Bake at 375°F (190°C) for 30 minutes.
Remove the foil and bake for another 15 minutes, until the cheese is golden and bubbly.
If you like a crisp top, broil for 2–3 minutes at the end to brown the cheese.
Step 6: Rest and serve
Allow the lasagna to rest undisturbed for 10 minutes before cutting into it.
This helps the layers set and makes serving easier.
Slice into generous squares, serve warm, and enjoy every creamy bite.
Recipe Variations: Make Chicken Alfredo Lasagna Your Own Pro Tips for Success
Let it rest before serving: Give the lasagna at least 10 minutes to set before slicing. It makes the layers hold beautifully.
Don’t skip the foil: Covering during the first bake keeps the lasagna creamy and prevents the top from drying out.
Pre-cook veggies: If you use mushrooms, zucchini, or broccoli, sauté them lightly first to avoid excess water in your lasagna.
Extra creamy sauce: Add a touch more cream or an extra handful of Parmesan if you love rich flavors.
Make ahead: Assemble the lasagna a day before, cover tightly, and refrigerate. Bake when ready to serve.
Flavor Variations
Broccoli Alfredo Lasagna: Swap spinach with blanched broccoli florets for a crunchier bite.
Mushroom Alfredo Lasagna: Add sautéed mushrooms for an earthy flavor.
Spicy Alfredo Lasagna: Stir a pinch of red pepper flakes into the Alfredo sauce.
Seafood Twist: Replace chicken with shrimp or crab for a luxurious version.
Cheesy Upgrade: Mix ricotta with cream cheese for an extra creamy layer.
Storage & Reheating Tips
Refrigerator: Keep leftover portions fresh in an airtight container for up to 3 days.
Freezer: Wrap securely and freeze for up to 2 months for longer storage. Thaw overnight before reheating.
Reheating: Gently warm in the oven at 350°F (175°C), covered with foil, until heated throughout.
Make It a Meal: Delicious Sides for Alfredo Lasagna
For me, lasagna is not just a main dish, it is an invitation to gather around the table, laugh, and share a generous moment. Here are a few ways to turn your Chicken Alfredo Lasagna into a complete and memorable meal.
Fresh & Light Sides
Garlic Bread – Warm, buttery, and crunchy on the outside, perfect for scooping up the creamy Alfredo sauce.
Caesar Salad – Crisp romaine with a zesty Caesar dressing balances the richness of the lasagna.
Roasted Vegetables – Asparagus, zucchini, or carrots bring color and freshness to the table.
Drinks to Pair
Sparkling Water with Lemon – A refreshing option that cuts through the richness.
Iced Tea – A family-friendly drink that complements the cozy feel of this dish.
Sweet Endings
Tiramisu Cups – A nod to Italy, light with a delicate coffee flavor.
Lemon Sorbet – Refreshing and citrusy, perfect for cleansing the palate.
Chocolate Mousse – A rich and decadent way to end the meal.
Make This Lasagna Your Next Family Favorite
Chicken Alfredo Lasagna is more than just a recipe—it is a balance of comfort, tradition, and a touch of creativity. Growing up in Italy, pasta has always been in my blood, and while I deeply respect the classics, I also love adding a new twist to something already extraordinary. This lasagna is exactly that: creamy, flavorful, and perfect for bringing people together.
Now it is your turn to try it in your own kitchen. Make it for a cozy weeknight dinner, a special family gathering, or simply when you crave something hearty and comforting. And remember, the best part about cooking is making a dish your own—so do not be afraid to add your personal touch.
If you try this recipe, I would love to hear from you. Leave a comment, share your variation, or let me know how your family enjoyed it. Recipes come alive when they are shared, and I cannot wait to see how this Chicken Alfredo Lasagna becomes part of your table.
Lasagna FAQ: Baking Times, Substitutions, and More
Q: Can you use Alfredo sauce for chicken lasagna? Yes. Alfredo sauce works perfectly for chicken lasagna, giving it a creamy base that pairs beautifully with shredded chicken and cheese.
Q: Can I use Alfredo sauce instead of béchamel in lasagna? A: Yes. Alfredo can replace béchamel, but note the difference: béchamel is milder and gives structure, while Alfredo is richer and cheesier. When substituting, make sure the Alfredo is not too heavy—thin with a little milk or broth if needed—and use it sparingly between layers so the lasagna does not become overly dense.
Q: What goes with chicken alfredo lasagna? A: Light, fresh sides balance the richness. Try garlic bread or crusty focaccia, a crisp Caesar or mixed green salad, and roasted vegetables like asparagus or zucchini. For drinks, a sparkling water with lemon pairs nicely. For dessert, lemon sorbet or tiramisu cups are great finishes.
Q: Can you use Alfredo sauce for lasagna with ricotta? A: Yes. Mixing Alfredo into ricotta makes a creamier, more flavorful ricotta layer. Example ratio: for 2 cups ricotta, stir in ½–1 cup Alfredo sauce plus ¼ cup grated Parmesan (season to taste). An optional egg can be added to help the ricotta set, but it’s not required.
Q: Do you put Alfredo in lasagna? A: Yes. Use Alfredo both as a base layer in the baking dish and between the pasta layers. Spread a thin layer on the bottom to prevent sticking, then add sauce between each noodle layer so the lasagna stays moist and creamy after baking.
Q: What is the best white sauce for lasagna? A: It depends on the dish. For a classic, light texture, béchamel (milk thickened with a roux) is best. For a rich, cheesy, chicken-forward lasagna, homemade Alfredo is the top choice. If you want creaminess without too much heaviness, use a blend: reduced béchamel or Alfredo thinned with broth.
Q: How long to bake lasagna? A: Preheat oven to 375°F (190°C). Cover the dish with foil and bake 30 minutes, then remove the foil and bake 15–20 minutes more until the cheese is golden and the sauce bubbles. Let the lasagna rest 10 minutes before slicing. Ensure the internal temperature reaches 165°F (74°C) for safe reheated/protein temperatures. If the lasagna is chilled or frozen, add about 10–20 minutes to the covered baking time.